Shortened silent period produced by magnetic cortical stimulation in patients with Parkinson's disease.
Nakashima K; Wang Y; Shimoda M; Sakuma K; Takahashi K
J Neurol Sci 1995 Jun;130(2):209-14

ABSTRACT: Magnetic Cortical Stimulation Can Produce Silent Periods (SP) Following Excitatory Motor Responses. In Patients With Parkinson's Disease (PD), A Shorter SP Was Observed. The Shortened SP In PD Patients Improved After Levodopa Administration. This Shortened SP In PD Patients May Be Related To The Hyperactivity Of The Motor Cortex, And To The Dopaminergic System. In Control Subjects, Sound Stimulation Produced Prolongation Of The SP At A Time Interval Of 100 Ms Between Sound And Magnetic Cortical Stimulation-increase In The Inhibitory Function. However, The Prolongation Of The SP After Sound Stimulation Was Not Observed In PD Patients Lack Of An Increase In The Inhibitory Function. Even After Levodopa Administration, Sound Did Not Prolong The SP In PD Patients. The Change Of The Auditory Effects On The SP May Be Due To The Abnormal Function Of The Reticular Formation In PD. This Change Might Be Independent Of The Dopaminergic System.MAIN MESH HEADINGS: Cerebral Cortex/*physiopathology
*Magnetics
Parkinson Disease/*physiopathology ADDITIONAL MESH HEADINGS: Acoustic Stimulation
Aged
Cerebral Cortex/drug Effects Dopamine/physiology Electromyography/drug Effects Female Human
Levodopa/pharmacology Male Middle Age Muscle Contraction/physiology Physical Stimulation
Reticular Formation/physiopathology
Support, Non-U.S. Gov't
1995/06
1995/01 00:00 PUBLICATION TYPES: CLINICAL TRIAL
JOURNAL ARTICLE CAS REGISTRY NUMBERS: 0 (Levodopa)
51-61-6 (Dopamine)
LANGUAGES: Eng

Voltar

 

Eletromagnetismo

Bioeletricidade
em Psiquiatría