Yawning and stretching induced by transcranial application of AC pulsed electromagnetic fields in Parkinson's disease.
Sandyk R
Int J Neurosci 1999 Mar;97(1-2):139-45

ABSTRACT:
Yawning Is Considered A Brainstem Regulated Behavior Which Is
Associated With Changes In Arousal And Activity Levels. Yawning
And Stretching Are Dopamine (DA) Mediated Behaviors And
Pharmacological Studies Indicate That These Behaviors Are
Associated With Increased DA Release Coupled With Stimulation
Of Postsynaptic DA-D2 Receptors. Despite Their Relation To The
Dopaminergic System, Yawning And Stretching Are Poorly
Documented In Untreated Or Treated Patients With Parkinson's
Disease (PD). A 49 Year Old Fully Medicated Female Patient With
Juvenile Onset PD Is Presented In Whom Recurrent Episodes Of
Yawning And Stretching Developed During Transcranial
Administration Of AC Pulsed Electromagnetic Fields (EM Fs) Of
Picotesla Flux Density. These Episodes Have Not Been Observed
Previously In This Or Other Patients During Treatment With
Levodopa Or DA Receptor Agonists Or In Unmedicated PD Patients
During Treatment With AC Pulsed EMFs. It Is Suggested That
Yawning And Stretching Behavior Resulted In This Patient From A
Synergistic Interaction Between EMFs And DA Derived From
Levodopa Supplementation With EMFs Possibly Facilitating The
Release Of DA And Simultaneously Activating Postsynaptic
DA-D2 Receptors In The Nigrostriatal Dopaminergic Pathways. In
Addition, It Is Postulated That The Release Of ACTH/MSH
Peptides From Peptidergic Neurons In The Brain Upon Stimulation
Of The DA-D2 Receptors Reinforced The Yawning And Stretching
Behavior.
MAIN MESH
HEADINGS:
*Electromagnetic Fields
Parkinson Disease/*physiopathology
Yawning/*physiology
PUBLICATION TYPES:
JOURNAL ARTICLE
CAS REGISTRY NUMBERS:
0 (Antiparkinson Agents)
0 (Receptors, Dopamine)
51-61-6 (Dopamine)
LANGUAGES: Eng

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Eletromagnetismo

Bioeletricidade
em Psiquiatría