Slow-frequency repetitive transcranial magnetic stimulation in a patient with focal cortical dysplasia.
Menkes DL; Gruenthal M
Epilepsia 2000 Feb;41(2):240-2

ABSTRACT:
PURPOSE: To Evaluate The Effect Of Slow-frequency Repetitive
Transcranial Magnetic Stimulation (SF-rTMS) On Interictal
Epileptiform Activity And Seizure Frequency In A Patient With
Medically Refractory Partial Seizures Due To Focal Cortical
Dysplasia. METHODS: A 9-cm Circular Coil Was Positioned Over
The Area Of Cortical Dysplasia. One Hundred Stimuli Given At 0.5
Hz At 5% Below Motor Threshold Were Given Biweekly For Four
Consecutive Weeks. The EEG Was Recorded For 30 Min Before
And After The First 100 Stimuli. The Number Of Seizures During The
Month Of Stimulation Was Compared With That Of The Month Before
Stimulation. RESULTS: Stimulation Was Associated With A 70%
Reduction In The Frequency Of Seizures And A 77% Reduction In
The Frequency Of Interictal Spikes. No Seizures Occurred During
Stimulation. CONCLUSIONS: SF-rTMS Was Safe And Well
Tolerated In This Patient. The Reduction In Seizures And Interictal
Spikes Associated With SF-rTMS Supports The Concept Of
SF-rTMS-induced Cortical Inhibition.
MAIN MESH HEADINGS:
Cerebral Cortex/*abnormalities
Epilepsies, Partial/*therapy
Magnetics/*therapeutic Use
PUBLICATION TYPES:
JOURNAL ARTICLE
LANGUAGES: Eng

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Eletromagnetismo

Bioeletricidade
em Psiquiatría