Shortened silent period produced by magnetic cortical stimulation in patients with Parkinson's disease.
Nakashima K; Wang Y; Shimoda M; Sakuma K; Takahashi K
J Neurol Sci 1995 Jun;130(2):209-14

ABSTRACT:
Magnetic Cortical Stimulation Can Produce Silent Periods (SP)
Following Excitatory Motor Responses. In Patients With
Parkinson's Disease (PD), A Shorter SP Was Observed. The
Shortened SP In PD Patients Improved After Levodopa
Administration. This Shortened SP In PD Patients May Be Related
To The Hyperactivity Of The Motor Cortex, And To The Dopaminergic
System. In Control Subjects, Sound Stimulation Produced
Prolongation Of The SP At A Time Interval Of 100 Ms Between
Sound And Magnetic Cortical Stimulation-increase In The
Inhibitory Function. However, The Prolongation Of The SP After
Sound Stimulation Was Not Observed In PD Patients Lack Of An
Increase In The Inhibitory Function. Even After Levodopa
Administration, Sound Did Not Prolong The SP In PD Patients. The
Change Of The Auditory Effects On The SP May Be Due To The
Abnormal Function Of The Reticular Formation In PD. This Change
Might Be Independent Of The Dopaminergic System.
MAIN MESH
HEADINGS:
Cerebral Cortex/*physiopathology
*Magnetics
Parkinson Disease/*physiopathology
ADDITIONAL
MESH HEADINGS:
Acoustic Stimulation
Aged
Cerebral Cortex/drug Effects
Dopamine/physiology
Electromyography/drug Effects
Female
Human
Levodopa/pharmacology
Male
Middle Age
Muscle Contraction/physiology
Physical Stimulation
Reticular Formation/physiopathology
Support, Non-U.S. Gov't
1995/06
1995/01 00:00
PUBLICATION
TYPES:
CLINICAL TRIAL
JOURNAL ARTICLE
CAS REGISTRY
NUMBERS:
0 (Levodopa)
51-61-6 (Dopamine)
LANGUAGES:
Eng

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Eletromagnetismo

Bioeletricidade
em Psiquiatría