Right frontal lobe slow frequency repetitive transcranial magnetic stimulation (SF r-TMS) is an effective treatment for depression: a case-control pilot study of safety and efficacy.
Menkes DL; Bodnar P; Ballesteros RA; Swenson MR
J Neurol Neurosurg Psychiatry 1999 Jul;67(1):113-5

ABSTRACT:
Major Depression May Result From Decreased Left Frontal Lobe
Function With Respect To The Right. Fast Frequency Repetitive
Transcranial Magnetic Stimulation (FF R-TMS) Excites The
Underlying Cortex Whereas Slow Frequency Repetitive
Transcranial Magnetic Stimulation (SF R-TMS) Causes Cortical
Inhibition. Left Frontal FF R-TMS Attenuates Major Depression
Whereas The Inhibitory Effects Of Right Frontal SF R-TMS Are
Unknown. This Study Tested The Hypothesis That Right Frontal SF
R-TMS Would Treat Depressed Patients With Minimal Effect On
Controls. A Psychiatrist Administered The Beck Depression
Inventory And Hamilton D Depression Rating Scales To Eight
Depressed Patients And Six Controls Before And After The
Treatment Protocol. Eight Sessions Of 100 Right Frontal Lobe SF
R-TMS Were Given At Motor Threshold And 0.5 Hz Over A 6 Week
Period. No Adverse Outcomes Were Noted In Either Group. A
Significant Antidepressant Effect Was Noted In Depressed Patients
On The Beck And Hamilton D Depression Rating Scales (p<0.05).
No Change On Either Scale Was Noted In The Controls. In
Conclusion Right Frontal Lobe SF R-TMS Is A Safe, Non-invasive
Treatment For Major Depression That Deserves Further
Investigation.
MAIN MESH
HEADINGS:
Depressive Disorder/*therapy
Frontal Lobe/*physiopathology
*Magnetics
PUBLICATION TYPES:
JOURNAL ARTICLE
LANGUAGES: Eng

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Eletromagnetismo

Bioeletricidade
em Psiquiatría